TCM Power Source Circuit [11/2021 - ]: Description
WARNING: This page is about a different car, the 2024 Lexus IS 500, 2023 Lexus IS 500, and 2022 Lexus IS 500. However, it is still accessible from the selected car via links, so may be relevant.
When the engine switch is turned on (IG), voltage from the ECM MREL terminal is applied to the EFI-MAIN relay. This causes the contacts of the EFI-MAIN relay to close, which supplies power to terminal +B of the TCM.