Conditions for Setting the DTC
WARNING: This page does not describe the selected car, but rather 8 other vehicles, including the 2012 GMC Yukon XL, 2012 GMC Yukon, 2012 Chevrolet Tahoe, 2012 Chevrolet Suburban, and 2012 Chevrolet Avalanche. However, it is still accessible from the selected car via links, so may be relevant.
The ECM detects that the actual measured values from the MAF sensor, MAP sensor, and throttle position sensor, are not within the range of the calculated values for V4 mode.