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DTC P0300 & P0301-P0304: Random Cylinder Misfire Detected: Notes

WARNING: This page is about a different car, the 2000 Honda Prelude. However, it is still accessible from the selected car via links, so may be relevant.
NOTE: DTC P0300 and some of DTCs P0301, P0302, P0303, and/or P0304 will set. If some of DTCs P0171, P0172, P0401, P0505, P1128, P1129, P1253, P1361, P1362, P1381, P1382, P1491, P1498, and/or P1508 are set with random misfire DTCs, trouble shoot these DTCs before random misfire DTCs.

If misfiring is frequent enough to trigger detection of increased emission during 2 consecutive driving cycles, Malfunction Indicator Light (MIL) will illuminate, and DTC P0300 and some combination of P0301-P0304 will be stored in memory. If misfiring is frequent enough to damage catalyst, MIL will blink whenever misfiring occurs, and DTC P0300 and some combination of P0301-P0304 will be stored in memory. When misfiring stops, MIL will still remain on.

Start engine and run at 3000 RPM with no loads and transmission in Park or Neutral until radiator fan comes on. Test drive vehicle to verify symptom. Perform inspection and repair procedures according to symptom. If misfire does not occur during test drive, check for low fuel quality (inadequate octane level), low fuel level, carbon on a spark plug, etc.