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DTC P0300: Random Misfire

WARNING: This page is about a different car, the 2006 Mercury Mariner and 2006 Ford Escape. However, it is still accessible from the selected car via links, so may be relevant.
P0300 - RANDOM MISFIRE

Description:  The random misfire DTC indicates multiple cylinders are misfiring or the PCM cannot identify which cylinder is misfiring.
Possible Causes: 
  • Camshaft position (CMP) sensor.
  • Low fuel, less than 1/8 tank.
  • Stuck open EGR valve.
  • Blocked EGR passages.
Diagnostic Aids:  One or more EGR passages may be blocked or partially blocked. If this is the case the misfire detection monitor indicates the EGR port to check for possible blockage.
Application  Key On Engine Off  Key On Engine Running  Continuous Memory 
All - GO to Pinpoint Test HD . GO to Pinpoint Test HD .