DTC P0300: Engine Misfire Detected: Description
WARNING: This page is about a different car, the 2003 GMC Sierra, 2003 GMC Cab & Chassis Sierra, 2003 Chevrolet Silverado, and 2003 Chevrolet Cab & Chassis Silverado. However, it is still accessible from the selected car via links, so may be relevant.
The ECM adjusts the fuel delivery to each cylinder in order to minimize crankshaft speed changes. If the ECM identifies a cylinder or cylinders requiring an excessive amount of fuel in order to maintain the correct crankshaft speed, DTC P0300 will set.